Here is the video showing John McCain answering this question from a supporter:

Ignoring the pot-meet-kettle hypocrisy of the questioner, I think McCain's response says a lot about his campaign, and who he has become.

I don't think he himself actually agrees with this characterization of Hillary Clinton. But he is definitely not comfortable with the question, and struggles to respond in a way that doesn't anger this room of wingnuts supporters. He wasn't about to chastise anyone for calling Hillary a bitch, not in that room. He wants to distance himself from such personal attacks, but knows that he needs just this kind of viciousness to win.

The Straight Talk Express crashed and burned a long time ago, if it existed at all.